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News articleYahoo Finance· January 21, 2026

Johnson & Johnson reports Q4 and Full-Year 2025 results

View original at finance.yahoo.com
Johnson & Johnson reports Q4 and Full-Year 2025 results 2025 Fourth-Quarter reported sales growth of 9.1% to $24.6 Billion with operational growth of 7.1%* and adjusted operational growth of 6.1%*; 2025 Fourth-Quarter earnings per share (EPS) of $2.10 and adjusted EPS of $2.46, both include $(0.10) due to the acquisiti…
Opening lines of the source · Yahoo Finance · short snapshot — read the full document at the original

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  • 2026 adjusted operational EPS guidance of $11.28-$11.48 with midpoint of $11.38 representing 5.5% growth

    80% confidence
  • 2026 adjusted EPS guidance of $11.43-$11.63 with midpoint of $11.53 representing 6.9% growth

    80% confidence
  • TREMFYA is the only IL-23 inhibitor proven to inhibit structural joint damage in active psoriatic arthritis

    80% confidence
  • INLEXZO achieved 74% disease-free survival at one year in BCG-unresponsive high-risk papillary-only NMIBC

    80% confidence
  • DARZALEX FASPRO is the first/only FDA-approved treatment for high-risk smoldering multiple myeloma

    80% confidence
  • 2026 adjusted operational sales growth guidance of 5.4%-6.4% with midpoint of 5.9%

    80% confidence
  • RYBREVANT FASPRO + LAZCLUZE has the shortest administration time for first-line combination regimen

    80% confidence
  • 2026 operational sales guidance of $99.5B-$100.5B with midpoint of $100.0B representing 6.2% growth

    80% confidence
  • TECVAYLI + DARZALEX FASPRO demonstrated superior PFS and OS vs. standard of care in second-line multiple myeloma

    80% confidence
  • Nipocalimab is the first/only investigational FcRn blocker showing potential to reduce SLE activity in Phase 2

    80% confidence
  • AKEEGA demonstrates 54% reduction in disease progression in BRCA2-mutated metastatic castration-sensitive prostate cancer

    80% confidence
  • 2026 reported sales guidance of $100.0B-$101.0B with midpoint of $100.5B representing 6.7% growth

    80% confidence
  • Subcutaneous amivantamab achieved 45% overall response rate with 7.2-month median duration in recurrent/metastatic head and neck cancer

    80% confidence

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Autumn 2026 Biopharma Catalyst Season: Late-Breaking Data, FDA Milestones and the Rise of AI-Designed Drugs
Late-September and early-October 2026 conferences (EASD, EADV, IGCS) brought a cluster of positive late-breaking trial readouts. These covered obesity and metabolic disease (Novo Nordisk's CagriSema), immunology (Lilly's EBGLYSS, tulisokibart) and oncology (Rina-S, Agenus BOT+BAL). Ahead lie hard regulatory catalysts, led by the 14 Nov 2026 FDA PDUFA date for ivonescimab. At the same time, Insilico-style AI-designed drugs such as rentosertib are showing anti-aging signals. That points to AI-driven drug discovery moving from concept toward clinical validation. Unrelated tech and regulatory items (Tesla Cybercab probe, xAI litigation, OpenAI agent incident) and the speculative QAIAx claims are peripheral to this story.
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
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ING Group
Both facts record the same metric (shares_outstanding) for ING Group at the identical observation date (2025-12-31). FACT A states 2,902,437,688 shares; FACT B states 2,902 million shares (2,902,000,000). The difference is 437,688 shares (~0.015%). This is a genuine value conflict, though the discrepancy appears to result from FACT B rounding to the nearest million while FACT A provides the precise count.
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